Find Kardus: Alprolix

Sunday, November 27, 2016

Alprolix

What Is Alprolix?

Coagulation factor IX is a man-made protein similar to a natural protein in the body that helps the blood to clot.
Coagulation factor IX is used to treat or prevent bleeding in people with hemophilia B. This medication is not for treating people with hemophilia A factor VIII deficiency.
Coagulation factor IX may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use this medicine if:

you have had an allergic reaction to clotting factor medicine;
you have signs of excessive blood clotting; or
you are allergic to hamster proteins.

To make sure coagulation factor IX is safe for you, tell your doctor if you have:

kidney disease;
liver disease;
coronary artery disease (hardening of the arteries); or
history of heart attack or stroke.

FDA pregnancy category C. It is not known whether coagulation factor IX will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether coagulation factor IX passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Coagulation factor IX is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

Alprolix Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; wheezing, tightness in your chest, difficult breathing, fast heartbeats, blue lips, feeling like you might pass out; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:

swelling in your feet or ankles, weight gain, loss of appetite;
fever or chills;
continued bleeding after treatment;
new or worsened bleeding; or
signs of excessive blood clotting--sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance, chest pain, coughing up blood, or pain, swelling, warmth and redness in one or both legs.

Common side effects may include:

nausea;
headache;
dizziness;
altered sense of taste;
mild skin rash; or
pain, stinging, or other irritation where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Alprolix Interactions

Follow your doctors instructions about any restrictions on food, beverages, or activity.
Other drugs may interact with coagulation factor IX, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Alprolix Dosage

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to quickly treat any serious side effects that occur.
Coagulation factor IX is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Coagulation factor IX is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
The mixture should appear clear and colorless. Do not use the mixed medicine if it has changed colors or has particles in it. Prepare a new kit or call your pharmacist for a new supply of coagulation factor IX.
Gently swirl but do not shake the medicine bottle when mixing or you may ruin the medicine. Use the injection within 3 hours after mixing your dose.
Coagulation factor IX comes with patient instructions for proper mixing and storage. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
While using coagulation factor IX, you may need frequent blood tests.
Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding disorder.
If you store this medicine at home, carefully follow the directions on your medicine label about how to store the powder medicine and the diluent. Some forms of coagulation factor IX can be stored at room temperature, and others should be kept in a refrigerator. Do not freeze. Avoid exposing the medication to sunlight.
Throw away any coagulation factor IX not used before the expiration date on the medicine label.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Contact your doctor for instructions if you miss a dose of this medicine.

download now